Neurology, Feb 2018

Journal Club: MRI reveals acute inflammation in cortical lesions during early MS.

Bateman EM, Schleicher WE, Smith EJ, Sweet DR, Gaudet AD.


Early multiple sclerosis is characterized by immune-associated demyelination of CNS axons. In a recent Neurology® article, Maranzano et al. evaluated MRI scans of patients with early multiple sclerosis to study the evolution of leukocortical lesions. Their novel data suggest that acute inflammation after blood-brain barrier leakage may contribute to gray matter cortical lesions in early multiple sclerosis.


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